Description
Associate Scientist – Target Discovery | Biotech | CHO Cell Lines | CRISPR
Location: Oxford
Salary: £34k - £37k + benefits
We’re hiring an Associate Scientist to join an innovative biotech team focused on advancing mammalian cell line development. If you're experienced in CHO cell culture and CRISPR gene-editing, and you're passionate about target discovery, this could be your next move.
What you’ll be doing:
- Designing and executing CHO cell culture experiments using small-scale and high-throughput models
- Running CRISPR knockout screens and transfections for gene editing
- Applying molecular and cell biology assays (qRT-PCR, Western blotting, ELISA)
- Operating the BD FACSAria Fusion Flow Cytometer for single cell cloning and analysis
- Supporting cell line development using technologies like Beacon and Ambr15
- Writing SOPs, maintaining lab documentation, and training junior scientists
- Ensuring lab safety standards and participating in out-of-hours cell culture as needed
What we’re looking for:
- BSc/MSc with 3+ years or PhD with 1+ years in a biotech or pharma environment
- Strong experience with CHO suspension cells, single-cell workflows, and genotyping
- Skilled in CRISPR/Cas9 techniques and FACS-based cell sorting
- Comfortable working independently and collaboratively in a fast-paced lab
- Experienced in experimental planning, troubleshooting, and scientific communication
Nice to have:
- Familiarity with Beacon, Ambr15, or 96-well high-throughput models
- Experience working safely with lentiviral plasmid systems in a CAT2 environment
- Understanding of monoclonal antibody production and critical quality attributes (CQA)
Looking to play a key role in breakthrough biologics research? Apply now!
